Phospho stat5 ihc

WebAlthough the mechanisms governing tyrosine phosphorylation and activation of Stat5b have been extensively studied, the role of serine phosphorylation remains to be fully elucidated. Using mass spectrometry and phospho-specific antibodies, we identified Ser-193 as a novel site of cytokine-induced phosphorylation within human Stat5b. WebStat5 has two isoforms, Stat5a and Stat5b. Aberrant Stat5 activation has been implicated in the pathogenesis of chronic myelogenous leukemia, prostate and breast cancer and …

Phospho-STAT5 expression is associated with poor …

WebPurity/Specificity. Phospho STAT5 pY694 was purified from concentrated tissue culture supernate by Protein A chromatography. This antibody is specific for mouse Stat5a protein phosphorylated at Y694. A BLAST analysis was used to suggest cross-reactivity with Stat5a from human, mouse and rat based on 100% homology with the immunizing sequence. optical group whitby https://liquidpak.net

Phosphotyrosine STAT5 ELISA Kit - RayBiotech

WebWe hypothesized that nuclear phospho-STAT5 (pSTAT5) in MCs might reflect TK activation and would be a marker of abnormal MCs in SM. Expression of tryptase, CD25, CD2 and pSTAT5 was evaluated by immunohistochemistry (IHC) on archival cases of SM and cutaneous mastocytosis (CM). pSTAT5 was detected in 23/23 of SM and 1/9 of CM MC … Web这种可以“不依赖于环境”的方式识别被修饰残基的能力使得这些抗体具有广泛反应性，从而可能使它们能够与成百上千的不同蛋白发生反应。. 这种广泛的反应性模式使得这些抗体对多重分析和靶标发现项目尤为有价值。. 描述：Cell Signaling Technology 抗体剂型为 ... WebDetection of Human Phospho-STAT5a/b (Y694/Y699) by Western Blot. ... (STAT5) is a member of the Jak/STAT signal transduction pathway and is activated by a variety of cytokines (IL‑22, IL-6, IFN-alpha ). STAT5 has two isoforms (A and B) that share 93% amino acid identity and bind the DNA consensus site TTCN 3 GAA. STAT5 mediates cytokine ... optical group canada

Detection of phospho-STAT5 in mast cells: a reliable

Category:Detection of phospho-STAT5 in mast cells: a reliable

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Phospho stat5 ihc

Phospho-STAT5 expression is associated with poor …

WebMay 20, 2009 · 11104 Background: EpoR mRNA and protein expression have been reported at low levels in human tumors implying EpoR may be functional in tumor cells with inferred implications for the use of erythropoiesis stimulating agents in the Oncology setting. However, mRNA studies use bulk tumor tissue which ignores contribution from the … WebMar 21, 2024 · The expression of STAT5 was thus the only noted difference in signaling proteins between HMC-1.2 and HMC-1.3 cells. However, the ratio of phospho-STAT5 to total STAT5 was similar in both cell lines with D816V (alone or in combination with V560G) (Figure 2C). Cells with gain-of function in KIT are known to appear refractory to SCF .

Phospho stat5 ihc

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WebMonoclonal Antibody for studying Bad (Ser99) phosphate. Cited in 1 publication. Highly specific and rigorously validated in-house, Phospho-Bad (Ser136) (5D8) Mouse Monoclonal Antibody (CST #5282) is ready to ship. WebMar 13, 2006 · Antibody against phospho-STAT5 (Cell Signaling Technology, Beverly, MA) was applied to IHC in a dilution of 1:50. IHC results were analysed for association with the …

WebStat transcription factors. Stat1 and Stat2 are induced by IFN-α and form a heterodimer which is part of the ISGF3 transcription factor comp WebExpression of tryptase, CD25, CD2 and pSTAT5 was evaluated by immunohistochemistry (IHC) on archival cases of SM and cutaneous mastocytosis (CM). pSTAT5 was detected …

http://bip.ihit.waw.pl/przetarg/items/648.html?file=tl_files/przetargi/2013/Przetarg%2016/Zalacznik%20nr%201.xls WebSRF-MRTFA复合物活性对Rho-GTPase诱导的细胞球状肌动蛋白 (G-actin)浓度变化作出反应，从而将细胞骨架基因表达与细胞骨架动力学耦合。. 心脏分化和成熟所必需的。. 产品编号. 产品名称. 包装. AG3308. SRF Mouse Monoclonal Antibody. 50µl. AZ050.

WebImmunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-STAT5 (phospho Y694) antibody [E208] - BSA and Azide free (ab219607) Immunohistochemistry …

WebPhospho-STAT5 alpha (Ser780) Polyclonal Antibody Catalog Number:PA5-36688 Product Data Sheet ... (IHC (P)) 1:50-1:200 Immunoprecipitation (IP) 1:50-1:200 * Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for … optical guidance systems telescopesWebKrólicze poliklonalne przeciwciało STAT3 (Ab-705), Ciężar molekularny 88KD, Aplikacja Western, IHC-Parafina, IF, 100ul Mysie monoklonalne przeciwciało NFkBp65(F-6), 1 ml Królicze monoklonalne przeciwciało Phospho-STAT3 (Tyr705) (D3A7), ... Królicze monoklonalne przeciwciało Phospho-STAT5 (Tyr694) (C11C5), Ciężar molekularny 90 … portishead model boat clubWebNov 12, 2024 · STAT (STAT1, STAT3, and STAT5) transcription factors regulate various biological processes such as the immune response and cell growth 7,8. STAT3 activation requires phosphorylation of a tyrosine ... optical gyroscope-on-a-chipWebPhospho-STAT5 alpha (Tyr694) Monoclonal Antibody (S.161.3) ... It is not recommended to aliquot this antibody. Background/Target Information STAT5 alpha is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are ... (IHC (P)) 1:600 Immunoprecipitation (IP) 1:50 optical group malaysiaWebRabbit polyclonal antibody raised against synthetic phosphopeptide of ABL1/ABL2. Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y393/Y429 of human ABL1/ABL2. (PAB12190) - Products - Abnova optical group indexWebPhospho-STAT5 alpha (Ser780) Antibody (PA5-36891) in IHC (P) Immunohistochemistry analysis of Phospho-STAT5 alpha (Ser780) in paraffin-embedded human lung carcinoma … optical guardWebAbstract The signal transducer and activator of transcription-5 (STAT5) protein has been shown to play an important role in tumor progression through stimulating cell proliferation and preventing apoptosis. STAT5 activation has been observed in a variety of human tumors and cancer cell lines. portishead market place