Chitinase-3-like protein 1

WebDiagnosis of cardiac surgery-associated acute kidney injury: differential roles of creatinine, chitinase 3-like protein 1 and neutrophil gelatinase-associated lipocalin: a prospective cohort study WebChitinase-3-like protein 1 (CHI3L1), also known as YKL-40, is a secreted glycoprotein that is approximately 40kDa in size that in humans is encoded by the CHI3L1 gene. The name YKL-40 is derived from the three N …

Chitinase-3 like-protein-1 function and its role in diseases

WebMar 4, 2024 · Chitinase-3-like protein 1 (CHI3L1) was induced in both acute and chronic liver injuries, and recent studies reported that it possesses an immunosuppressive ability. CHI3L1 was also expressed in mesenchymal stem cells (MSCs), thus we investigates the role of CHI3L1 in MSC-based therapy for immune-mediated liver injury here. We found … WebBackground: Chitinase 3-like 1 protein (CHI3L1) (YKL-40 in humans and breast regression protein [BRP]-39 in mice) is required for optimal allergen sensitization and Th2 inflammation in various chronic inflammatory diseases including asthma. However, the role of CHI3L1 in airway inflammation induced by respiratory viruses has not been investigated. church arrangements/floral https://liquidpak.net

Intact regulation of muscle expression and circulating levels of ...

WebChitinase 3-like 1 (CHI3L1) is a chitinase-like protein, which affects cel … The cancer‑stromal interaction has been demonstrated to promote tumor progression, and … WebUrine chitinase 3-like. Background Acute kidney injury (AKI) is a frequently occurring syndrome in critically ill patients and is associated with worse outcomes. Biomarkers allow early identification and therapy of AKI which may improve outcomes. ... Urinary cell cycle arrest biomarkers and chitinase 3-like protein 1 (CHI3L1) to detect acute ... WebFeb 1, 2024 · The differentially secreted proteins of M1 and M2 macrophages were analyzed by mass spectrometry. We performed GST pull-down assay for the identification of cell-membrane receptors that interact with chitinase 3-like protein 1 (CHI3L1) protein. The mouse model was used to validate the function of CHI3L1 in cancer metastasis in vivo. church arson act

CHI3L1 - Wikipedia

Category:Chitinase 3-like 1 suppresses injury and promotes fibroproliferative ...

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Chitinase-3-like protein 1

Chitinases and Chitinase-Like Proteins in Obstructive Lung …

WebChitinase 3-like 1 (CHI3L1), also called BRP39 in mouse or YKL-40 in humans, is a 39 kDa glycoprotein member of the glycosyl hydrolase 18 family although it does not show … WebNational Center for Biotechnology Information

Chitinase-3-like protein 1

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WebDec 1, 2024 · Chitinase-3 like-protein-1 (CHI3L1), a member of glycoside hydrolase family 18 including chitinases and non-enzymatic chitinase-like proteins, is a secreted molecule that plays an important role in cancer development, inflammatory diseases and oxidant injury via various mechanisms [8]. WebFeb 19, 2024 · Systemic sclerosis (SSc) is an autoimmune disease with completely undefined etiology and treatment difficulties. The expression of both protein coding and non-coding RNAs is dysregulated during disease development. We aimed to examine a …

WebChitinase 3-like 1 (CHI3L1) is a secreted glycoprotein that mediates inflammation, macrophage polarization, apoptosis, and carcinogenesis. The expression of CHI3L1 is … WebApr 6, 2024 · IntroductionPositive intracranial arterial remodelling is a dilated lesion of the large intracranial vessels; however, its pathogenesis is currently unknown. Some studies …

WebUrine chitinase 3-like. Background Acute kidney injury (AKI) is a frequently occurring syndrome in critically ill patients and is associated with worse outcomes. Biomarkers … WebChitinase 3-like 1: Products. Chitinase 3-like 1 (CHI3L1), also called BRP39 in mouse or YKL-40 in humans, is a 39 kDa glycoprotein member of the glycosyl hydrolase 18 family …

WebChitinase-3-like protein 1 (YKL-40, also named human cartilage glycoprotein 39) is a mammalian glycoprotein related in sequence to family 18 of bacterial and fungal …

WebSep 14, 2024 · Non-enzymatic chitinase-3 like-protein-1 (CHI3L1) belongs to glycoside hydrolase family 18. It binds to chitin, heparin, and hyaluronic acid, and is regulated by … detmer from discoveryWebAnti-Chitinase-3-like protein 1 (YKL-40) Antibody, clone mAY. Compare Product No. Clonality Application Species Reactivity Citations SDS; MABC196: mAY, monoclonal: IHC, WB, activity assay: human: 6: Expand. Hide. Match Criteria: Product Name, Keyword. All Photos (1) Human CHI3L1 / Chitinase-3-like Protein 1 ELISA Kit. Compare Product No ... det merit and equityWebMar 8, 2024 · Chitinase-3-like 1 protein (YKL-40) is a secreted glycoprotein originally isolated from human osteosarcoma cells . YKL-40 is approximately 40 kDa in size and is … church artifact long darkWebJul 6, 2024 · Here, we show that chitinase-3-like 1 (CHI3L1), also known as human homolog YKL-40, predominately modulates the GBM TME using unbiased approaches. CHI3L1 signaling selectively regulates tumor infiltration and cell migration of MDMs and MG by forming distinct protein-binding complexes. church arsonWebChitinase-3-like protein 1 (CHI3L1) is a secreted glycoprotein characterized by its ability to regulate multiple biological processes, such as the inflammatory response and gene transcriptional signaling activation. Abnormal CHI3L1 expression has been associated with multiple neurological disorders and serves as a biomarker for the early ... churchart pro clip artWebIntroduction. Chitinase-3-like protein 1 (CHI3L1), also known as YKL-40 and human cartilage glycoprotein-39 (HC-gp39), is a highly conserved glycoprotein that can bind to heparin, chitin and collagen. 1,2 CHI3L1 plays an important role in tissue inflammation, tissue remodeling, fibrosis and cancer. 3–5 Current studies have reported that serum … church articles of incorporation sampleWebMay 9, 2024 · Background and objectives: Multiple sclerosis (MS) is an autoimmune disease confined in the CNS, and its course is frequently subtle and variable. Therefore, predictive biomarkers are needed. In this scenario, we conducted a systematic review and meta-analysis to evaluate the reliability of chitinase 3-like 1 as a biomarker of MS. church articles of incorporation texas