Biochemical freedom from failure
WebDec 1, 2003 · Freedom from biochemical failure was defined as a serum PSA level of ≤0.5 ng/mL at last follow-up. Patients were censored at last follow-up if their serum PSA level was still decreasing. Patients whose serum PSA level reached a nadir at a value >0.5 ng/mL were scored as having failure at the time at which their PSA reached a nadir. WebMulticenter Analysis of Effect of High Biologic Effective Dose on Biochemical Failure and Survival Outcomes in Patients With Gleason Score 7–10 Prostate Cancer Treated With Permanent Prostate Brachytherapy Nelson N. Stone, Louis Potters, Brian J. Davis, Jay P. Ciezki, ... Richard G. Stock
Biochemical freedom from failure
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WebJan 1, 2008 · Background: The American Society for Therapeutic Radiology and Oncology (ASTRO) definition of biochemical failure (BF) incorporates backdating, resulting in an artificial flattening of Kaplan-Meier curves and overly favorable estimates when follow-up is short. The nadir + 2 ng/mL (Nadir + 2; Phoenix) definition reduces these artifacts. The … WebNov 1, 2000 · Freedom from biochemical failure was defined as a serum PSA < or = 0.5 ng/mL at last follow-up. The biochemical control rate at 3 years for all 499 patients was 86%, with 348 patients followed ...
WebBiochemical freedom from failure (BFFF) was computed by the Phoenix definition, freedom from metastasis (FFM) in men with BF by absence of a positive bone or CT … WebThe primary endpoint was freedom from failure (FFF), with failure defined as clinical or biochemical failure. Two definitions of biochemical failure were used: the American Society for Therapeutic Radiology and Oncology definition (three consecutive increases in prostate-specific antigen level) and the Phoenix definition (nadir plus 2 mu g/L).
WebFeb 1, 2009 · Patients were stratified on the basis of age: {<=}60 (n = 378) and >60 years (n = 1,287). Biochemical failure was defined as a prostate-specific antigen (PSA) nadir plus 2 ng/mL. Univariate and multivariate analyses were used to determine the association of variables with freedom from biochemical failure (FFbF). WebMay 9, 2024 · BCR = biochemical recurrence BED = biologically effective dose bFFF = biochemical freedom from failure bPFS = biochemical progression-free survival BT = brachytherapy CSS = cancer-specific survival DE-EBRT = dose-escalated external beam radiation therapy DFS = disease-free survival EORTC = European Organization for …
WebNov 11, 2014 · Kaplan–Meier estimates of freedom from biochemical failure (FFBF) were used to describe the patients overall, and comparisons were accomplished using log-rank statistics (16, 17). Simple Cox proportional hazards regression modeling was used to estimate hazard ratios for categorical variables of interest. The overall sample was …
WebRates of freedom from biochemical failure (biochemically no evidence of disease [bNED]) varied considerably from one series to another and were highly dependent on tumour stage, grade and pretreatment serum prostate-specific anti-gen (PSA) levels. Results in patients with favourable tumours (T1 or T2 tumour, chippea hotmail.comWebNov 2, 2007 · The end point for the trial was biochemical freedom from failure, and follow-up ranged from 2 to 16 years (median, 5 years). The researchers found that young men had biochemical outcomes... granty sport prahaWebMar 25, 2024 · The Seattle Isotope trial randomized low-risk prostate cancer pts to I-125 vs. Pd-103 and found no difference in 3-yr biochemical freedom from failure (89% vs. 91%, p = 0.76) and no ... Younger pts appear more likely to have a bounce. Bounces of >2 ng/mL (i.e., biochemical failure by Phoenix definition) may occur in 15% of pts. However, PSA ... chippeakanno packageWebJun 30, 2015 · The primary endpoint was 24 month biochemical freedom from failure (the “Phoenix” definition). Subjects underwent biopsy for cause (rising PSA) or at the end of study (24 months). Adverse events were assessed at each postoperative visit and reported as mild, moderate or severe and related to the device or procedure at 24 months. ... grantys liberecWebApr 12, 2024 · And this civilizational failure of nerve and moral exhaustion is leaving us vulnerable to our global enemies. If and when we go, the long great political experiment––freedom and equality and self-rule for all regardless of birth, wealth, or education–– will finally end in failure and despotism. The bad omens abound. chip peak annotationWebDec 1, 2012 · Freedom from biochemical failure (FFBF), freedom from local failure (FFLF), and freedom from distant failure (FFDF) were analyzed. Results: In a median … chip peachWebWith longer follow-up, Tendulkar and colleagues 83 demonstrated an improvement in metastasis-free survival in addition to biochemical recurrence. The freedom from biochemical failure decreased from 71% for those with a presalvage PSA of 0.01 to 0.2 … Peyman Hadji, in Marcus and Feldman's Osteoporosis (Fifth Edition), 2024. … With a median follow-up of 7.8 years, 10-year freedom from biochemical failure … granty sport